The 4-star L'Isola Che C'E Hotel Cagliari is situated within 5 minutes' walk of the Anfiteatro Romano and provides shuttle service, along with bicycles for rent. Located within a few blocks of the Clemente Susini anatomical wax models, this Cagliari guest house features a safe deposit box and 24-hour security service.

The hotel is about 5 km from Elmas airport and a mere 150 metres from such cultural venues as the ancient Roman Amphitheatre of Cagliari. There is the Church of Sant'Efisio a stone's throw from the L'Isola Che C'E Cagliari. The accommodation is also just 1.4 km from the Bastion of Saint Remy and Yenne bus station is merely a 5-minute walk away.

The allergy-friendly rooms comprise a kitchenette and a dining area, and offer a flat-screen TV with satellite channels along with a minibar fridge and coffee/tea making facilities. Bedrooms come with extra-long beds or sofa beds. Bathroom facilities include a bidet, a walk-in shower, and a separate toilet, as well as comforts such as a hair dryer and free toiletries.

Guests can enjoy a selection of Mediterranean dishes at Ristorante Ammentos situated a short way from L'Isola Che C'E Hotel.